Molly Shannon

Mary Katherine Gallagher

Will Ferrell

Sky Corrigan / Jesus

Elaine Hendrix

Evian

Harland Williams

Slater

Mark McKinney

Father Ritley

Glynis Johns

Grandma

Jason Blicker

Howard

Gerry Bamman

Father John

Emmy Laybourne

Helen

Jennifer Irwin

Maria

Rob Stefaniuk

Thomas

Natalie Radford

Autum

Karyn Dwyer

Summer

Tom Green

Dylan

Chuck Campbell

Owen

Jack Newman

Mr. Feinstein

Donna Hanover

Mrs. Corrigan

Dan Redican

Freaky Freddy

Joan Massiah

Crucifix Nun

Jean Howell

Moira McDaniels

Frank Scott

George

Mallory Margel

Little Mary

Deirdre McCloskey

Rosemary Gallagher

David Warrack

Father David

Aidan Kelly

Thornton Gallagher

Jane Moffat

Sister Eileen

Tracy Wright

Sister Anne

Robert Clark

Little Boy Slater

Rick Campanelli

Reporter

Ariel Manson-Wagner

Reporter

Boyd Banks

Weatherman

Sal Scozzari

Special Ed Kid

Christina Gordon

Special Ed Kid

Susie Dias

Special Ed Kid

David Meinke

Special Ed Kid

Tina Campbell

Cheerleader

Christine Nowland

Cheerleader

Carole Mackereth

Cheerleader

Michael McCloskey

Shamus O'Shea

Blake Brooker

Man with Cake

Joanna Bennett

Student (uncredited)

Gabriel Burrafato

Todd (uncredited)

Phil Crowley

Etiquette Record (voice) (uncredited)

Spencer Humm

Choral Singer (uncredited)

Fraser McGregor

Bike Boy (uncredited)

April Morgan

Dancer (uncredited)

Jonathan Gabriel Robbins

Tom, Whose Dad Is Dead (uncredited)

Jason Sehorn

Man in Pink Tutu (uncredited)